Background: External environmental influences can cause an increased generation of reactive oxygen species in the body, which overwhelm the body's own antioxidant enzyme systems. The result is oxidative stress, which can damage cells and organs which then might cause neuronal dysfunction and even neurodegenerative and neuroinflammatory processes. The Gitterchip technology by QiBlanco as used in the QiHome® Air forms a static field that stimulates water molecules to undergo a transition into the coherent state. Since our body consists of about 70-85% of water, the coherent state of the water molecules should be able to influence the cells of our whole body in a positive manner against environmental influences.

Experimental: Based on the knowledge of neurodegeneration and neuroinflammation, neuronal cells (SH-SY5Y cells) and inflammation-mediating cells (HL-60 cells differentiated to functional neutrophils) were used in this in vitro study.

Results: The QiHome® Air had positive effects on all parameters tested in this in vitro study compared with untreated controls. Peripheral neuronal cell regeneration was significantly improved by 53.3 ± 6.4 % compared to untreated control cells (p ≤ 0.01; Wilcoxon-Mann-Whitney two-tailed rank sum test). In addition, also neuronal cell viability/survival after environmental oxidative stress was markedly increased by the QiHome® Air exposure compared to untreated controls by 34 % at 1 mM hydrogen peroxide and more than 80 % at 1.5 mM hydrogen peroxide (p ≤ 0.01). Compared to the untreated controls, exposure to the QiHome® Air resulted in a pronounced and statistically significant increase (p ≤ 0.01) in the basal metabolism of functional neutrophils by 20.7 ± 8.0 %. In contrast, the generation of reactive superoxide anion radicals was significantly reduced by the QiHome® Air by 16.4 ± 4.1 % compared to the untreated controls (p ≤ 0.01)

Conclusions: Oxidative stress plays a central role in the damage of peripheral and central nerve cells and the development of many neurological disorders and diseases. As demonstrated in the cell-based assays presented here, exposure to the QiHome® Air has beneficial properties that might counteract environmental disturbances leading to neurodegeneration, neuroinflammation and the associated functional disorders in a complex organism, thus, maintaining and improving individual well-being and neuronal health.