“Astrocyte-neuron” Interaction Promoted by Moxibustion in Alzheimer’s Disease: Evidence from Spatial Transcriptomics

Yuan Shen1, Lushuang Xie2, Qiaofeng Wu1,*

Abstract

Alzheimer’s disease (AD), the most common type of dementia, is an irreversible neurodegenerative disease.
Due to the increased incidence and the lack of specific therapeutics, it seems very important to understand it’s
pathology and find useful treatments. Fortunately, clinical and experimental studies have shown that moxibustion
provided good therapeutic effects on AD. Here, we also discovered that “astrocyte-neuron” interaction played a vital
role in central nervous system for moxibustion in AD.