Neurodegenerative Diseases: Current Research

Targeting Riboflavin Receptor 3 in Neurological Diseases

Jindian Li^1,2, Xianzhong Zhang^2,*, Kai Chen^1,*

¹Department of Radiology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
²Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen 361102, China

Abstract

Neurological diseases are widespread and serious global illnesses. Neurons highly rely on aerobic metabolism in mitochondria. Riboflavin receptor 3 (RFVT3) is a vital section of the mitochondrial network, which plays a key role in riboflavin homeostasis and the production of adenosine triphosphate (ATP). The abnormal expression of RFVT3 is closely associated with the occurrence and progression of multiple neurological diseases. Therefore, it is crucial to explore the dynamic expression of RFVT3 for the diagnosis and treatment of neurological diseases.

Keywords: