Neurodegenerative Diseases: Current Research

“Astrocyte-neuron” Interaction Promoted by Moxibustion in Alzheimer’s Disease: Evidence from Spatial Transcriptomics

Yuan Shen¹, Lushuang Xie², Qiaofeng Wu^1,*

¹Acupuncture and Moxibustion School, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China
²College of Basic Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China

Abstract

Alzheimer’s disease (AD), the most common type of dementia, is an irreversible neurodegenerative disease.
Due to the increased incidence and the lack of specific therapeutics, it seems very important to understand it’s
pathology and find useful treatments. Fortunately, clinical and experimental studies have shown that moxibustion
provided good therapeutic effects on AD. Here, we also discovered that “astrocyte-neuron” interaction played a vital
role in central nervous system for moxibustion in AD.

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